We now treat our dogs today as family, and that shift has reshaped the entire pet wellness industry. Owners are no longer satisfied with basic treats. They’re looking for products that actively support dental health, digestion, mobility, and long-term wellbeing.
The numbers reflect this shift. The U.S. dog treats, chews, and toppers market reached $7.9 billion in 2025 and is projected to grow to $15.9 billion by 2035, according to industry market analysis. Dental chews alone account for a major portion of that growth, driven by rising awareness of oral hygiene and its connection to overall canine health.
With so many brands offering functional treats and supplement-style chews, choosing the right option can be difficult. Ingredient quality, nutritional benefits, and product formulation all matter. This guide reviews the most recognized dog supplement and chew brands available today. Each brand is evaluated based on ingredient transparency, functional benefits, and reputation within the pet wellness industry.
Why Functional Dog Treats Are Growing in Popularity
Functional treats and supplement-style chews are becoming a core part of modern dog care routines. Dental chews alone represent 23% of growth in the dog treat category, largely because pet owners are paying closer attention to plaque control and fresh breath. Many products now incorporate ingredients that target multiple wellness benefits at once.
Scientific research also supports the role of nutrition in canine health. A 2022 randomized placebo-controlled study published in PLoS ONE found that dogs with osteoarthritis experienced significant improvement in mobility and pain scores when given supplements containing ingredients such as glucosamine, collagen, and Boswellia serrata.
Another study published in Frontiers in Veterinary Science in 2025 demonstrated that joint supplements containing eggshell membrane and omega-3 fatty acids improved mobility and pain outcomes in dogs over a 90-day period.
These findings reinforce a broader trend that many pet owners now use supplements and functional chews proactively to support long-term health.
Top Dog Supplement Brands in 2026
1. Pup Labs
Pup Labs is a premium wellness brand that focuses on functional dog supplements, dental chews, and health-supporting treats designed to promote overall canine wellbeing.
Instead of sticking to traditional snack-style treats, you can shop Pup Labs online for science-guided formulations and natural ingredients that support multiple areas of dog health, including digestion, oral hygiene, and stress reduction.
Key Features:
- Natural ingredients without artificial additives or fillers
- Dental chews designed to help reduce plaque and tartar buildup
- Probiotics and prebiotics that support digestive balance
- Functional treats that can assist with training and behavioral reinforcement
Best For:
Pet owners who want multifunctional treats that combine dental care, digestive support, and everyday rewards in one routine.
Standout Quality:
The brand’s approach combines functional health benefits with everyday treat use, allowing dogs to receive nutritional support during normal feeding and training routines rather than through separate supplement regimens.
2. Greenies
Greenies is one of the most widely recognized dental chew brands in the United States. Its toothbrush-shaped treats are designed to help clean teeth while dogs chew, making them popular among owners focused on oral hygiene.
Key Features:
- Textured chew design that reaches along the gumline
- Veterinary Oral Health Council (VOHC) recognition for plaque control
- Multiple size options for different breeds
- Variety of flavors including chicken and blueberry
Best For:
Owners prioritizing dental health who want a chew specifically designed for plaque and tartar reduction.
3. Milk-Bone
Milk-Bone is one of the longest-standing dog treat brands in the market. Known for its crunchy biscuits and dental chews, it remains a popular choice due to its wide availability and recognizable flavors.
Key Features:
- Crunchy biscuits that help clean teeth during chewing
- Fortified with vitamins and minerals such as A, E, and B12
- Multiple treat varieties including brushing chews and soft snacks
- Widely available in large multi-pack sizes
Best For:
Pet owners seeking familiar, widely accessible treats that offer basic nutritional benefits.
4. Zuke’s
Zuke’s has built a reputation for natural training treats and active-lifestyle dog nutrition. Its Mini Naturals treats are particularly popular among trainers due to their small size and high protein content.
Key Features:
- Real meat is the primary ingredient in many formulas
- Low-calorie training treats designed for frequent rewards
- Added antioxidants such as blueberries and turmeric
- Grain-free options available
Best For:
Active dogs and training environments where small, frequent treats are used.
5. Blue Buffalo
Blue Buffalo is widely known for premium pet foods, but it also produces a variety of functional dog treats and chews that mirror its ingredient philosophy.
Key Features:
- Real chicken or beef as primary ingredients
- Added omega fatty acids for skin and coat health
- Antioxidant blends that support immune function
- Grain-free options available
Best For:
Owners already using Blue Buffalo foods who want treats that align with the same ingredient standards.
What to Look for in a Dog Supplement Brand
Dog supplements and functional chews should provide more than flavor. The best options support a dog’s health through carefully selected ingredients and purposeful formulations.
Ingredient quality is one of the most important factors. Natural proteins, vitamins, and probiotics support digestive balance, immune health, and energy levels. Avoid artificial preservatives and fillers to reduce the risk of sensitivities in dogs.
Functional health benefits are another key consideration. Modern supplements often target specific needs such as dental hygiene, joint mobility, digestive health, or stress management.
Digestibility and safety also matter. Veterinarians frequently advise pet owners to choose reputable brands that use ingredients proven to be safe and easily digestible for dogs.
Finally, breed size compatibility and chew durability play a role. Small breeds require softer or smaller treats, while aggressive chewers benefit from longer-lasting options that help reduce boredom and destructive behaviors.
Conclusion
The dog supplement and functional treat market continues to evolve as owners place greater emphasis on long-term wellness and preventative care. High-quality ingredients, targeted health benefits, and reputable manufacturing practices all contribute to identifying trustworthy brands. Dental health support, digestive balance, and mobility care are now common priorities in modern dog nutrition.
For pet owners exploring supplement-style treats, understanding ingredient quality and intended health benefits can make choosing the right product much easier. As the industry continues to expand, brands that combine nutritional science with everyday usability will likely define the next generation of canine wellness products.
References
- Creevy, K. E., et al. (2025). Dog Aging Project TRIAD Trial: Investigating rapamycin for extending canine healthspan and lifespan. AVMA News.
- Martello, E., Bigliati, M., Adami, R., et al. (2022). Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial. PLOS ONE, 17(2), e0263971.
- Ragetly, G. R., Martins, Â., Ober, C. A., et al. (2025). Efficacy of a joint supplement containing eggshell membrane among other ingredients to improve the mobility of dogs with osteoarthritis: A multicenter double-blind randomized placebo-controlled study. Frontiers in Veterinary Science, 12, 1561793.
- Colorado State University Veterinary Teaching Hospital. (2026). Orthomed joint supplement clinical trial for dogs with osteoarthritis.
- National Institutes of Health. (2025). Dog Aging Project receives $7M grant to study rapamycin’s impact on aging in dogs.
- U.S. Pet Food Market Analysis. (2025). U.S. dog treats, chews, and toppers market growth report 2025–2035. Pet industry market research report.
- Veterinary Oral Health Council. (2024). VOHC accepted products for plaque and tartar control in dogs.